EndoCannabinoids are fatty neuro transmitting or messaging molecules synthesized by our bodies as an adaptive response to cellular stress, aimed at reestablishing cellular homeostasis. Or . . . cannabinoids are the language our bodies use on the cellular level to communicate states of health or dis-ease and call the body to make changes. Their main pathway of affect is the Receptors, but that is only one of many strategies of action our body uses.
These are molecules our bodies make as part of this communication system. They are synthesized on demand from precursors in the cell membrane. The precursors are derivates of Omega 6 fatty acid. Built when needed, have their affect, and then are quickly degraded and the components recycled.
These are molecules released by a cell either to regulate that cell’s own (autocrine) physiology to bring it back into balance, or to do so for one of its neighboring cells (paracrine).
They are the mechanism our bodies have developed and maintained over 600,000,000 years to communicate and correct imbalances. These imbalances can be within the cell or in the environment around the cells. This is done at a core level of cellular communication. Because it is so deep in our physiology, and has been present so long, a nearly magical complexity has developed through all the strategies used in its pursuit of its function in reestablishing homeostasis.
In 1992 the first Endocannabinoid was discovered. It was named Anandamide. It was named after the Sanskrit word for Bliss, Ananda. It fits into the CB1 receptor, like a lock and key.
Anandamide is also found in the Black Truffle.
2 AG, a second Endocannabinoid was discovered a few years later. 2AG is like THC in that it binds to both Receptors.
There are numerous other Endocannabinoids besides the two, we just know very little about them at this time.